Proteins weight lifting with

Stepwise increases in oil-like character, as when the mildly oil-like Val (V) residue is replaced by the very oil-like Phe (F) residue, cause the add-base titration curves to be shifted to higher pH values and to be steeper. The energy required to drive the model protein from the phase separated, contracted state to the swollen, relaxed state is proportional to the width of the curve, that is, inversely proportional to the steepness of the curve. Accordingly, the model protein with the steepest curve exhibits the most efficient function for performing the work of lifting a weight. 

It has now been possible to stretch a single elastic protein-based polymer chain and to obtain a uniformly increasing force versus extension curve.This was done with a surprisingly simple device called an atomic force microscope, the development of which resulted in the Nobel prize for Paul Hansma. The performance of the mechanical work of lifting a weight, shown in... 

Obviously, the effect of raising the temperature of a loaded, cross-linked elastic band composed of elastic protein-based polymers of the poly(GVGVP) family is to drive hydrophobic association with the consequence of lifting of the attached weight. How does this combine with the above understanding of elasticity to perform mechanical work ... 

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