Proteins supercomplexes, organization

Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes Implications for Lipid-Linked Disorders... 

This review will focus on a combination of molecular genetic and biochemical studies on the role of primarily phosphatidylethanolamine (PE) and cardi-olipin (CL) in the folding and organization of individual membrane proteins and multicomponent supercomplexes. The results of such studies will be related to the known and possible involvement of lipids in diseases resulting from lack of proper organization of membrane proteins. Rather than being an inclusive review of protein-lipid interactions, the aim is to select specific well-documented examples of lipid-protein interactions to illustrate the broader role of lipids in determining cellular function. 

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