Proteins acid secretory response

In polymorphonuclear leucocytes (PMNL, neutrophils), secretory responses measured as vitamin B -binding protein release were inhibited by feverfew extract when the response was induced by the chemotactic peptide FMLP or arachidonic acid but not when the calcium ionophore A23187 was... 

Figure 9-4. Acid secretory equivalent of 29 common foods in relation to their protein content. The total acid secreted by a dog s Pavlov pouch in response to a 100-kcal meal of any of the 29 foods was divided by the total acid secreted by the same dog s pouch in response to a 100-kcal meal of boiled ground beef. The quotient, multiplied by 100, is the acid secretory equivalent for 100 kcal of that particular food. The foods used ranged from canned peaches, containing the least protein per 100 kcal, to haddock, with the most protein per 100 kcal. (Adapted from St Hilaire S, Lavers MK, Ken-nedey J, et al. Gastric secretory value of different foods. Gastroenterology 39 1-11, 1960.)...

Fig. 8.1 A schematic diagram illustrating the involvement of NF-k I in gpl20, ROS, NO, PG, IL-1/3 and TNF-a-mediated neurotoxicity. NMDA-R, N-Methyl-D-aspartate receptor, cPLA2, cytosolic phospholipase A2 lyso-PtdCho, lysophosphatidylcholine AA, arachidonic acid cAMP, cyclic adenosine monophosphate PKA, protein kinase A TNF-a, tumor necrosis factor-a TNF-a-R, TNF-a-receptor IL-1/8, interleukin-1 /3 IL-l/i-R, IL-1/8-receptor, IL-6, interleukin-6 MARK, mitogen-activated protein kinase NO, nitric oxide PG, prostaglandins EP-R, prostaglandin receptors NF-kB, nuclear factor-icB NF-kB-RE, nuclear factor-/cB-response element I/cB, inhibitory subunit of NF-icB HIV-1, human immunodeficiency virus type 1 gpl20, HIV-1 coat glycoprotein COX-2, cyclooxygenase-2 iNOS, inducible nitric oxide synthase SPLA2, secretory phospholipase A2 SOD, superoxide dismutase MMP, matrix metalloproteinase and VCAM-1, vascular adhesion molecule-1...

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