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Protein tyrosine phosphate

Zhang and co-workers worked on the structure-based, computer-assisted search for low molecular weight, non-peptidic protein tyrosine phosphate IB (PTPIB) inhibitors, also using the DOCK methodology [89], They identified several potent and selective PTPIB inhibitors by saeening the ACD. [Pg.616]

PTP protein tyrosine phosphate or protein tyrosine phosphatase... [Pg.362]

A number of other factors, including some growth factors, may act in a manner similar to insulin, causing phosphorylation of proteins on both tyrosine and serine moieties, and having protein tyrosine phosphate phosphatase activity. [Pg.440]

ATP + protein tyrosine = ADP + protein tyrosine phosphate (<1> regulation of mitosis, differentiation, migration, neovascularization, and apoptosis [40] <1> PTKs are closely related with cell groth, proliferation, differentiation and signalling of the immune system)... [Pg.490]

ATP -h protein tyrosine <322-324> (some kinases are able to phosphory-late both serine/threonine and tyrosine, <322> [667] specificity, <324> [682] structure-fmction relationship, <324> [683] in vitro specificity, <324> [689] <322> overview of the best studied protein targets of src kinases, functions [708]) [667-669, 680, 682, 683, 685, 688-690, 692, 708] ADP -I- protein tyrosine phosphate... [Pg.541]

Rahman, S.M. Dobrzyn, A. Dobrzyn, P Lee, S.H. Miyazaki, M. Ntambi, J.M. Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphate IB in muscle. Proc Natl Acad Sci USA 2003,100,11110-11115. [Pg.274]


See other pages where Protein tyrosine phosphate is mentioned: [Pg.230]    [Pg.230]    [Pg.92]    [Pg.163]    [Pg.491]    [Pg.491]    [Pg.532]    [Pg.532]    [Pg.532]    [Pg.533]    [Pg.533]    [Pg.540]    [Pg.541]    [Pg.541]    [Pg.541]    [Pg.541]    [Pg.142]    [Pg.406]    [Pg.1895]    [Pg.352]    [Pg.1430]   
See also in sourсe #XX -- [ Pg.5 , Pg.174 , Pg.182 ]




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