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Protein irradiation, temperature effect

Patten F, Gordy W. Temperature effects on free radical formation and electron migration in irradiated proteins. Proc. Natl. Acad. Sci. U.S.A. 1960 46 1137-1144. [Pg.26]

The radiation inactivation process involves Q, the average amount of radiation energy required to inactivate one mole of protein (Kepner and Macey, 1968). Q for radical formation, one of the steps leading to protein inactivation, is temperature dependent (Muller, 1962). Beauregard and Potier (1985) proposed that the effect of temperature on Q is directly responsible for the temperature dependence of protein inactivation, as revealed by the variation of D37, since the number of hits (or ionizations) per unit mass of the sample is temperature independent (Lea 1955 Augenstein and Mason, 1962). Thus the efficiency of a hit to result effectively in the inactivation of a molecule depends on the irradiation temperature. From Kepner and Macey (1968) and Jung (1984), we rewrite equation (4) to take the temperature into account ... [Pg.317]

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See also in sourсe #XX -- [ Pg.44 ]



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