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Protein-embedded reference materials

STANDARD REFERENCE MATERIAL PROTEIN-EMBEDDING TECHNIQUE AND DESIGN OF BAR CODE... [Pg.141]

Figure 8.3 Diagram depicts major experimental steps for validation of the protein-embedding barcode used as standard reference material for standardization/quantita-tive immunohistochemistry. [Pg.148]

It is important to recognize that establishing a model reference material, such as the protein-embedding model described above, while essential, is just the first step for standardization of IHC. Further studies will be required to develop mathematically conversion factors, and to explore the potential utility and limitations of this approach for different proteins that are of clinical interest, as diagnostic, prognostic, or predictive markers, as described above.1012... [Pg.149]


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Materials protein

Protein-embedded reference materials standardization

Standard reference material protein-embedding technique

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