Protein adsorption mechanism schematic

Figure 3 is a schematic of the proposed adsorption mechanism. Once a protein molecule arrives at the interface, it unfolds in an attempt to adapt to the new microenvironment. During the course of an adsorption experiment and at a certain point on the reaction coordinate, a pseudo, reversible phase equilibriiun should adequately represent the situation existing between the bulk phase and the interface (Fig. 3a). For the purpose of analysis, this state of equilibrium can be resolved into two major subequilibrium states (Fig. 3b) ...

Figure 4.1 The biomimetic advantages of nanomaterials. (a) The nanostructuied hierarchical self-assembly of bone, (b) Nanophase titanium (top, atomic force microscopy image) and nanocrystalline HA/ helical rosette nanombe (HRN) hydrogel scaffold (bottom, scanning electron microscopy (SEM) image), (c) Schematic illustration of the mechanism by which nanomaterials may be superior to conventional materials for bone regeneration. The bioactive surfaces of nanomaterials mimic those of natural bones to promote greater amounts of protein adsorption and efficiently stimulate more new bone formation than conventional materials. Zhang, L., Webster, T.J., 2009. Nanotechnology and nanomaterials promises for improved tissue regeneration. Nano Today 4, 66-80.

---