Protease inhibitors specific agents

Protease inhibitors are often incorporated into the comprehensive treatment of people with HIV infection. Use of these drugs in combination with other anti-HIV agents is discussed in more detail later in this chapter (see HIV and the Treatment of AIDS ). In addition, a specific protease inhibitor can be combined with a low dose of ritonavir—a process known as protease-inhibitor boosting. 34,69 Ritonavir inhibits the hepatic breakdown of the other (primary) protease drug, thereby enabling the primary drug to exert better therapeutic effects at a lower dose.34... 

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