Prostin VR Pediatric

Children Caverject is not indicated for use in newborns or children. However, alprostadil Prostin VR Pediatric) is used in newborns to maintain the patency of the ductus arteriosus in neonates with congenital heart defects. 

Penile injection (Caverject, Edex) 5, 10, 20, 40 meg sterile powder for reconstitution Parenteral (Prostin VR Pediatric) 500 mcg/mL ampules Bimatoprost (Lumigan)... 

The ductus arteriosus in neonates is highly sensitive to vasodilation by PGEj. Maintenance of a patent ductus may be important hemodynamically in some neonates with congenital heart disease. PGEj (alprostadil, prostin vr pediatric) is highly effective for palliative, but not definitive, therapy to maintain temporary patency until surgery can be performed. Apnea is observed in —10% of neonates so treated, particularly those who weigh <2 kg at birth. 

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