2-Propyn-l-ols

Propyn-l-ol Alkali metals, mercury(II) sulfate, oxidizing materials, phosphorus pentoxide, sulfuric acid... 

Propargyl Alcohol. Propargyl alcohol [107-19-7] 2-propyn-l-ol, C H O, is the only commercially available acetylenic primary alcohol. A... 

Propargyl alcohol (2-propyn-l-ol) [107-19-7] M 56.1, b 54 /57mm, 113.6 /760mm, d 0.947, n 1.432. Commercial material contains a stabiliser. An aqueous soln of propargyl alcohol can be concentrated by azeotropic distn with butanol or butyl acetate. Dried with K2CO3 and distd under reduced pressure, in the presence of about 1% succinic acid, through a glass helices-packed column. 

Whereas the Rh2(OAc)4-catalyzed addition of diazoalkanes to propargyl alcohols readily gives the insertion of the carbene into the 0-H bond, with only a small amoimt of cyclopropenation of the resulting propargylic ether [54] the 2-diazopropane 59 reacts at 0 °C with l,l-diphenyl-2-propyn-l-ol 62a in dichloromethane and exclusively gives, after 10 h of reaction, only the adduct 63a isolated in 75% yield and corresponding to the regioselective 1,3-dipolar cycloaddition of the 2-diazopropane to the alkyne C - C bond (Scheme 15). 

F. B. Growcock and V. R. Lopp. The inhibition of steel corrosion in hydrochloric acid with 3-phenyl-2-propyn-l-ol. Corrosion Sci, 28(4) 397-410,1988. 

Potassium permanganate Potassium sodium alloy 2-Propyn-l-ol Organic or readily oxidizable materials Air, carbon dioxide, carbon disulfide, halocarbons, metal oxides Alkali metals, mercury(II) sulfate, oxidizing materials, phosphorus pentoxide, sulfuric acid... 

Scheme 1 Synthesis of the allenylidene complex 1 from l,l-diphenyl-2-propyn-l-ol...

Synonyms Ethynol carbinol acetylene carbinol propiolic alcohol 2-propyn-l-ol 2-propynyl alcohol... 

Copper(I) acetylide is used in a diagnostic test for CH unit to prepare pure copper powder in purification of acetylene and as a catalyst in the synthesis of acrylonitrile and 2-propyn-l-ol. 

The reaction is based on the spontaneous dehydration of the intermediate hydroxyvinylidene species formed, either via A or via B (Scheme 2.1), after the coordination of 2-propyn-l-ols at the metal center. 

Some of these complexes have also been used as suitable precursors of related allenylidenes obtained through substitution or insertion reactions (see below). Other synthetic approaches to achieve selectively C/C substituted allenylidenes from reactions of dilithium derivatives Li2[C=CCR20]> obtained by deprotonation of 2-propyn-l-ols, with [M(CO)5(THF)] (M = Cr, W) and subsequent deoxygenation with phosgene are not always straightforward [10]. 

Other synthetic methodologies have been used to prepare the unusual octahedral osmium(II) allenylidenes [OsH(=C=C=CPh2)(NCMe)2(PiPr3)2][BF4] and [Os k (C,0)-C(C02Me)=CH2 (=C=C=CPh2)C0)(PiPr3)2][BF4] from l,l-diphenyl-2-propyn-l-ol [22]. 

Taking advantage of the regioselectivity shown by the indenyl-ruthenium(II) complexes [Ru(q -C9H7)(=C=C=CR R )(PPh3)2][PF6] an efficient synthetic procedure for the propargylic substitution of 2-propyn-l-ols mediated by the metallic... 

Preparation of alkenylcarbene metal complexes was reported by Le Bozec and Dixneuf et al. in 1991 by activation of propargylic alcohols in the presence of methanol [13[. Thus, photolysis of M(CO)6 (M = Cr, W) in the presence of 2-propyn-l-ol derivatives 30 in the presence of MeOH gave the corresponding... 

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