Propyl Magnesium Bromide

Dimethyl n-propyl carbinol, CH3(CH2)2COH(CH3)2. From n-propyl magnesium bromide and acetone. Collect the tertiary alcohol at 121-124°. 

Fluorosalicylaldehyde 1-Chloro-2-hvdroxv-3-t-butylaminopropane Propyl Magnesium Bromide... 

Ethylenedioxy-60(-methylandrost-4-ene-3,17-dione Propyl magnesium bromide Acetic acid... 

Propyl Magnesium Bromide Sodium hydride Flydrogen chloride... 

When bromine or bromine water is added to mercury dipropyl, or the base is treated with hydrobromic acid, propyl mercuric bromide is obtained in leaflets, M.pt. 138° C. The compound is also formed as a by-product in the preparation of mercury diproj yl from propyl magnesium bromide and mercuric bromide. ... 

Propyl silicon trichloride is formed by the action of propyl magnesium bromide on silicon tetrachloride, and is a clear, colourless liquid, B.pt. 128° to 125° C. In preparing the chloride all traces of moisture must be absent. It has a penetrating odour and fumes in the air. By allowing the liquid to drop into ice-water, the acid, PrSiO. OH, is obtained, and with anhydrous alcohol the trichloride gives silicon propyl triethyi ester, PrSi(OEt)3. 

Phenylethylpropylchlorosilicane is the principal product from the interaction of phenylethylsilicon dichloride and propyl magnesium bromide. Its boiling-point is not very definite (about 250° to 260° C.), and it is a colourless, refractive, mobile liquid, fuming in air, and readily decomposed by water. 

Benzylethylpropylchlorosilicane is produced from benzylethyl-silicon diehloride (1 mol.) and propyl magnesium bromide (1 mol.). It is a colourless, fuming, mobile liquid, which generally becomes pink, and is immediately decomposed by water, yielding the corresponding silicol and oxide. It boils at 172° to 176° C. at 50 mm., and the yield is 50 to 60 per cent, of the theoretical. 

From benzylethylsilicone, C5H5CH3.C2H5.SiO, and propyl magnesium bromide. The mixture is heated to 190 C, then decomposed by water. ... 

PROBLEM 14.5 Write the structure of the product of the reaction of propyl-magnesium bromide with each of the following. Assume that the reactions are worked up by the addition of dilute aqueous acid. 

Reaction of allylic alcohols with Grignard reagents. The reaction of n-propyl-magnesium bromide with allylic alcohols in the presence of catalytic amounts of dichlorobis(triphenylphosphine)nickel leads to a mixture of olefins derived from the alcohol 2 for example ... 

Isopropylidenetriphenylphosphorane in tetrahydrofuran mixed with an equimolar amount of ethyl chloroformate, allowed to stand a few hrs., 3 moles n-propyl-magnesium bromide added, and refluxed ca. 5 hrs. isopropyl -propyl ketone. Y 58%. F. e. s. T. Mukaiyama, R. Yoda, and I. Kuwajima, Tetrah. Let. 1969, 23... 

Very recently, pentaalkylcorannulene derivatives were used as initiators to generate corannulene-core polymers by expansion of live pendant groups (Scheme 14) [97]. The first initiator 45-PrOH was prepared by the Fe-catalyzed Kumada coupling of 46 with (3-((triisopropylsilyl)oxy)propyl)magnesium bromide, as presented in Scheme 13, and subsequent desilylation. The second initiator 45-PrE was obtained by the reaction of 45-PrOH with a-bromoisobutyryl bromide. 

Mercaptobenzylamine hydrodiloride added to a soln. of 3 moles n-propyl-magnesium bromide prepared from Mg and n-propyl bromide in tetrahydro-furan, gently warmed for 5 hrs., benzotridiloride added, and refluxed 5 hrs. 

D Hollander and Anteunis mention the use of gas chromatography in the analysis of n-propyl magnesium bromide. They reacted the organomagnesium compound with an excess of diisopropyl ketone to form a compound which at elevated temperatures produces propylene in almost quantitative yield. The propylene was determined gas chromatographically,... 

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