Propionitrile Propynal

Propionitrile can be obtained as the major product (70%) on passing mixtures of propyne and NH, over ZnClj/sUica gel at 360-380°C [229]. 

Comparison of the different types of cobalt catalysts shows that the in situ system [Eq.(2)] is most accessible while the Rep-, R(ind)-, and bori-ninato ligands having electron-withdrawing substitutents are the most active. The difference between the 14e" and the 12e core complexes makes itself apparent in the chemoselectivity of the reaction. Catalysts containing a 14-electron core favor pyridine formation, whereas those containing a 12-electron core (i.e., the rj -allylcobalt systems) favor the formation of benzene derivatives by cyclotrimerization of the alkynes. For example, in the reaction of propyne and propionitrile at 140°C in the presence of a 12-electron system (5), a 2 1 ratio of benzene to pyridine product is formed, whereas a catalyst containing the cpCo moiety (a 14-electron system) leads (under identical conditions) to the predominant formation of pyridine derivatives (84HCA1616). 

Propargyl bromide Propyne, 3-bromo- (8) 1-Propyne, 3-bromo- (9) (106-96-7) Tributyltin hydride Stannane, tributyl- (8,9) (688-73-3) Azobisisobutyronitrile Propionitrile, 2,2 -azobis[2-methyl- (8) Propanenitrile, 2,2 -azobis[2-methyl- (9) (78-67-1)... 

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