Progression of Drug Metabolism

C.D. Klassen, D.L. Eaton, and S.Z. Cagen, Hepatobiliary disposition of xenobi-otics, in J.W. Bridges, and L.F. Chasseaud, eds., Progress in Drug Metabolism, John Wiley Sons, New York, 1981. 

Babany, G. Larrey, D. Pessayre, D. (1988) Macrolide antibiotics as inducers and inhibitors of cytochrome P-450 in experimental animals and man. In Progress in Drug Metabolism, (ed. G.G. Gibson), pp. 61-98. Taylor and Francis, London. 

DR Hawkins. The role of stable isotopes in drug metabolism. In JW Bridges, LF Chasseaud, eds. Progress in Drug Metabolism. Bristol, UK Wiley, 1977, pp 163—218. 

LEWIS, D.F.V. (1990) MO-QSARs a review of molecular orbital-generated quantitative structure-activity relationships. In Progress in Drug Metabolism, edited by G.G.Gibson (London Taylor Francis). 

Understanding the metabolic fate of a drug and routes of elimination early in drug development can provide valuable information for further development. Such information can help identify the potential for drug interactions in humans, explain interindividual and ethnic differences, and indicate the need for further pharmacological characterization or structure modification. Rapid progress in the inclusion of drug metabolism studies in development is attributable to three factors ... 

Preece NE and Timbrell JA (1990) Use of NMR spectroscopy in drug metabolism studies recent advances. Progress in Drug Metabolism 12 147-203. 

Bourne, G.R. (1981) The metabolism of P-adrenoreceptor blocking drugs. Progress in Drug Metabolism, 6,77-110. 

---