Processes that take Place in an LC Column

Dispersion Processes that take Place In an LC Column 

There are four basic dispersion processes that can occur in a packed column that will account for the final band variance. They are namely, The Multipath Effect, Longitudinal Diffusion, the Resistance to Mass Transfer in the Mobile Phase and the Resistance to Mass Transfer in the Stationary Phase. All these processes are random and essentially noninteracting and, therefore, provide individual contributions of variance that can be summed to produce the final band variance. Each process will now be discussed individually. 

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