Process analytical technology food chain

Quality control at every step of the manufacturing chain must be adapted to the needs of a growing market where products must be manufactured in a fast and robust manner. The concept of global quality control by assessing quality at every step of the production chain was introduced by the U.S. Food and Drug Administration (FDA), which launched the process analytical technology (PAT) initiative to transform approaches to quality assurance in every step of the process [1]. This initiative encourages the implementation of three basic ideas [2] ... 

In 1995, the amendments to the Clean Air Act included requirements for maximum achievable control technology (MACT) for pollutants, including dioxins and metals. The EPA has since promulgated regulations that will have to be met by a modified baseline process for the Pueblo site (EPA, 1999). In addition, EPA is reviewing the effects of dioxins on human health because some evidence indicates dioxins may be more harmful in the food chain than previously thought (Kaiser, 2000). If dioxin emission standards are modified, analytical procedures will need to be reviewed. 

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