Preprothrombin antibodies

Preprothrombin can be determined immunologically, either using antiprothrombin antibodies, after adsorption of the y -carboxylated protein onto barium carbonate or using anti-preprothrombin antibodies that do not cross-react with prothrombin. Circulating concentrations of preprothrombin in vitamin K deficiency are of the order of 150 to 1,500 nmol per L. If elevated preprothrombin is because of vitamin K deficiency, then it will fall on administration of the vitamin, whereas if it is the result of liver disease, then vitamin K supplements will have no effect. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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