Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Preparation of 19-Norsteroids from 19-Substituted Steroids

The routes published by Syntex and by CIBA are very similar Syntax route  [Pg.265]

Reductive opening with zinc and isopropanol or acetic acid is possible either at the bromo ether stage or at the a,/5,-unsaturated keto [Pg.265]

Several variants of the above schemes have been investigated. Examples are the reversal of the oxidation (at C-3) and reduction steps [of the 5a-bromo ethers (2)] °  [Pg.266]

Again reductive opening of the lactone ring can be achieved at the chloro lactone or a,j5-unsaturated keto lactone stages.  [Pg.266]

Note 1. Amalgamated zinc can be used for the same purpose. [Pg.267]

Preparation of 19-norsteroids from 19-substituted steroids by solvolytic cleavage... [Pg.453]

Preparation of 19-norsteroids from 19-substituted steroids by transformations of 6/3, 19-ethers reductive cleavage of 5o -bromo-6/3,19-ethers, 266... [Pg.453]

III. Preparation of 19-Norsteroids from 19-Substituted Steroids / 264 Transformations of 6(3, 19-ethers / 264 Transformation of 19-oximino derivatives / 268 Removal of the C-10 substituent / 272 Summary and procedures for 19-norsteroids / 278... [Pg.244]

See other pages where Preparation of 19-Norsteroids from 19-Substituted Steroids is mentioned: [Pg.264]    [Pg.140]    [Pg.264]    [Pg.140]   


SEARCH



19-Norsteroids

19-norsteroid

Of steroids

Preparation of 19-norsteroids

Steroid substitution

© 2024 chempedia.info