Preparation by Enantioselective Catalysis

In addition to metal-catalysed reactions, it has been found that enzymatic catalysis is also an effective tool for some transformations leading to some types of enantioenriched P-stereogenic compounds. 

In this chapter, catalytic methods for ligand synthesis are described in detail. In spite of that, the enantioselective deprotonation of tert-butyldimethylpho-sphine borane with a catalytic amount of (—)-sparteine or a (+)-sparteine surrogate, reported by O Brien and co-workers, is included for convenience in Chapter 5, Section 5.4.2, following the discussion on the general strategy of desymmetrisation by enantioselective deprotonation. The coverage of Section 6.2 is mainly limited to systems in which the chiral catalyst acts in the step where the 

P-Stereogenie Ligands in Enantioselective Catalysis By Arnald Grabulosa Arnald Grabulosa 2011 

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