Pregnenolone-16-carbonitrile, cytochrome

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Elshourbagy, N.A. and PS. Guzelian (1980). Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile. J. Biol. Chem. 255, 1279-1285. 

Hardwick, J.P., EJ. Gonzalez, and C.B. Kasper (1983), Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16 alpha-carbonitrile. Characterization of its mRNA, gene, and induction response. J. Biol. Chem. 258, 10182-10186. 

Schuetz, E.G., S.A. Wrighton, J.L. Berwick, and P.S. Guzelian (1984). Induction of cytochrome P-450 by glucocorticoids in rat liver. 1. Evidence that glucocorticoids and pregnenolone 16 alpha-carbonitrile regulate de novo synthesis of a common form of cytochrome P-450 in cultures of adult rat hepatocytes and in the liver in vivo. J. Biol. Chem. 259, 1999-2006. 

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