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Pregnane characterization

Koyano, S., Kurose, K., Saito, Y., et al. (2004) Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR) one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region. Drug Metab. Dispos. 32, 149-154. [Pg.72]

Zhang J, Kuehl P, Green ED, Touchman JW, Watkins PB, et al. 2001. The human pregnane X receptor genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics 11 555-72... [Pg.306]

Ap-59 Okumura, T., Nozaki, Y., and Satoh, D., Chem. Pharm. Bull. (Tokyo) 1, 1143 (1964). 3i3,l4j3,21-Trihydroxy-5/3-pregnan-20-one gave IjS-hydroxylation with Absidla orchldis From 4,5-dehydrodlgltoxlgenone the 7/3-hydroxy and 7/3,12/3-dihydroxy products were characterized,... [Pg.725]

Maurel,M. Relling, C. Brimer,K. Yasuda,S. A. Wrighton, M. Hancock, R. B. Kim, S. Strom, K. Thummel, C. G. Russell, /. R. Hudson, /r., E. G. Schuetz, and M. S. Boguski, Pharmacogenetics, 11, 555 (2001). The Human Pregnane X Receptor Genomic Structure and Identification and Functional Characterization of Natural Allelic Variants. [Pg.411]

See other pages where Pregnane characterization is mentioned: [Pg.421]    [Pg.293]    [Pg.315]    [Pg.29]    [Pg.282]    [Pg.369]    [Pg.262]    [Pg.165]    [Pg.198]    [Pg.768]    [Pg.245]    [Pg.304]    [Pg.322]    [Pg.327]    [Pg.329]    [Pg.421]    [Pg.367]    [Pg.323]    [Pg.441]    [Pg.206]    [Pg.461]    [Pg.453]    [Pg.198]    [Pg.268]    [Pg.269]    [Pg.302]    [Pg.343]    [Pg.3]    [Pg.421]    [Pg.325]    [Pg.1317]    [Pg.139]    [Pg.461]    [Pg.98]    [Pg.609]    [Pg.900]    [Pg.8]    [Pg.57]    [Pg.155]    [Pg.723]    [Pg.2450]    [Pg.378]    [Pg.389]    [Pg.349]    [Pg.47]   
See also in sourсe #XX -- [ Pg.293 ]



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Pregnan

Pregnane

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