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Prazosin HCl

Prazosin hydrochloride (2[4- (2-furoyl)piperazin-l-yl 4-amino-6,7-dimethoxyquinazoline hydrochloride) [19237-84-4] M 419.9, m 278-280°, 280-282°, pK s 6.5. The salt is recrystallised by dissolving it in hot MeOH, adding a small volume of MeOH/HCl (dry MeOH saturated with dry HCl gas) followed by dry Et20 until crystallisation is complete. Dry it in vacuo over solid KOH till the... [Pg.695]

The antihypertensive drug prazosin 283 has been labelled with C by reacting C-Iabelled methyl iodide with desmethylated compound 284 prepared from 283 HCl by stirring it with 1.1 equivalent of BBrj in CH2CI2 under N2 (equation 112). The specific activity of 283 10 min after the end of a 25 min synthesis was 3500 Ci mmol". ... [Pg.1205]

See other pages where Prazosin HCl is mentioned: [Pg.1676]    [Pg.1676]    [Pg.329]    [Pg.329]    [Pg.1676]    [Pg.1676]    [Pg.329]    [Pg.329]    [Pg.561]    [Pg.507]    [Pg.507]    [Pg.561]    [Pg.680]   
See also in sourсe #XX -- [ Pg.894 ]

See also in sourсe #XX -- [ Pg.894 ]



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Prazosin

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