Practical Tips for Increasing Proficiency

Thus far, we have only explored a limited number of reactions, and the complexity of synthesis problems is therefore limited. At this stage, it might be difficult to see why retrosynthetic analysis is so critical. However, as we expand our repertoire of reactions, we will begin to explore the synthesis of more sophisticated structures, and the need for retrosynthetic analysis will become more apparent 

The functional groups in the precursor serve as handles enabling formation of the strategic bond (utilizing a reaction that we will 

As we move through the text, both fists will grow. For solving synthesis problems, it will be helpful to have the reactions categorized in this way in your mind. 

choose another reaction, perhaps another alkylation  

treat the alkyne with another reagent. Look at the list of reactions of alkynes and choose one perhaps hydrogenation with a poisoned catalyse 

---