Postsynthetic modification types

Numerous examples of postsynthetic modifications at the dendritic periphery have been explored. In early work, Hawker et al. investigated the hydro-genolysis and subsequent modification of benzyl-protected poly(aryl ester) dendrimers473 and later the saponification of Frechet-type dendrimers with p-methyl benzoate end groups to afford an anionic carboxylated periphery.41 The isophthalate ester end groups proved to be especially versatile (Scheme 28)... 

Stubinitzky C, Cserep GB, Batzner E, Kele P, Wagenknecht HA (2014) 2 -Deoxyuridine conjugated with a reactive monobenzocyclooctyne as a DNA building block for copper-free click-type postsynthetic modification of DNA. Chem Commun 50(76) 11218-11221. doi 10.1039/c4cc02855d... 

Figure 3.7 Grafting (postsynthetic functionalization) for organic modification of mesoporous pure silica phases with terminal organotrialkoxysilanes of the type (R 0)3SiR. R = organic functional group.

Depending on in situ and postsynthetic treatment procedures, azomethine-type tetrachloroisoindolinone pigments may result in several crystal modifications, e.g., in a, y, and 5 types [13], Mono and disazomethine pigments feamring heterocyclic ring systems have also been claimed by several companies [14], The heterocyclic stmcmre 18 even features two pigment chromophores, namely the qui-nophthalone and the isoindoHnone moieties [15]. 

---