Porphyrinogen, ring synthesis

Porphyrin, 5,10,15,20-tetraphenyl-, 4, 386 Porphyrin, vinyl-synthesis, 4, 278, 279 Porphyrin coenzymes in biochemical pathways, 1, 258-260 Porphyrinogen, mcso-tetraaryl-synthesis, 4, 230 Porphyrinogens, 4, 378, 394 pyrazoles, 5, 228 synthesis, 4, 231 Porphyrins, 4, 377-442 acetylation, 4, 395 aromatic ring current, 4, 385 basicity, 4, 400 biosynthesis, reviews, 1, 99... 

The next reaction of heme synthesis is catalyzed by 8-ALA dehydratase, in which two molecules of 8-ALA condense to form the pyrrole, porphobilinogen (Fig. 44.5). Four of these pyrrole rings condense to form a linear chain and then a series of porphyrinogens. The side chains of these porphyrinogens initially contain... 

---