Pore partitioning hydrodynamic modeling

To evaluate the solute diffusion coefficient in the stationary phase, and the solute partition coefficient, fCq, a model for the pore is required. A simple model where the pore is considered as an infinitely long cylinder and the solute is a rigid sphere adequately describes the elution process [58]. Using this model, Dg, the solute diffusivity within the porous particles, can be estimated from the hydrodynamic theory of hindered diffusion [59] ... [Pg.15]

Transport through nanofiltration membranes is controlled primarily by electrostatic and steric interactions. The extended Nemst-Plank equation commonly is used with Donnan and steric partitioning to predict transport rates based on effective membrane charge density, pore radius, and thickness to porosity ratio [131-132]. Inclusion of solute-pore hydrodynamic interactions and a pore size distribution improves the predictive and correlative capabilities of the models [133]. [Pg.320]