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Pore formation, freeze drying

Fig. 4 Formation process of a pore by cryogelation (a) and by freeze-drying (b). Red, green, and gray circles represent monovinyl monomers, divinyl monomers, and polymer repeat units, respectively... Fig. 4 Formation process of a pore by cryogelation (a) and by freeze-drying (b). Red, green, and gray circles represent monovinyl monomers, divinyl monomers, and polymer repeat units, respectively...
Another scaffold fabrication technique is thermally induced phase separation (TIPS) [34,46,84,147-149]. TIPS involves decreasing the temperature of a polymer solution to obtain a polymer-rich and polymer-poor phase. Following phase separation, the solvent is removed using one of a number of methods (freeze drying, evaporation) resulting in the formation of pores in the polymer stracture. TIPS can also be combined with the use of porogens to increase void fraction, have better control over pore size, or improve pore interconnectivity. [Pg.90]


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Freeze drying

Freeze-dried

Freeze-dry

Freezing freeze drying

Freezing pores

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