Pore Cholesterol-binding toxins

When alamethicin is added to a ternary vesicle system comprising PDA, phospholipid, and lipopolysaccharide (LPS), the addition of polymyxin, an LPS-binding antibiotic, sensitizes the vesicles to alamethicin (Katz et al. 2003). Cholesterol-containing PDA liposomes have been used to colorimetrically detect streptolysin O, a cholesterol-dependent pore-forming toxin (Ma and Cheng 2005). 

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