Pondimin

Pesos (Valeas) Ponderal (Servier) USA Pondimin (Robins)... 

After many health problems and deaths, the FDA removed Pondimin and Redux from market. Since then, there have been 200 reported cases of primary pulmonary hypertension relating to fen-phen and dexfen-phen. Of those cases, 40 have resulted in death. The FDA has received more than 100 reports of heart valve damage directly related to fen-phen or fenfluramine therapy there are no reports from individuals taking phentermine alone for weight loss. 

Fenfluramine hydrochloride Pondimin Wyeth-Ayerst Appetite suppressant 6/14/1973 9/15/1997 23.25 years Valvular heart disease Not available... 

On September 15,1997, FDA asked the manufacturers of dexfenfluramine (Redux manufactured for Intemeuron Pharmaceuticals by Wyeth-Ayerst) and fenfluramine (Pondimin Wyeth-Ayerst) to voluntarily withdraw both treatments from the market because of findings that indicate approximately 30% of patients taking the combined drugs had abnormal echocardiograms, even if they had no symptoms. Both companies agreed. FDA is not requesting the withdrawal of phentermine, the third widely used medication for obesity. 

Redux(tm) and Pondimin(tm) were voluntarily withdrawn in September 1997 because 30% of the patients taking these two dmgs had abnormal echocardiograms, 2004. See... 

Fenfluramine (Pondimin) and phentermine (Adipex-P, Fastin) are anorexigenic drugs that produce depression of the CNS and at one time were used (Fen-phen) in the treatment of obesity. Sibutramine (Meridia) is also available for the treatment of obesity. 

Off-label use during the 1990s became an issue after doctors in the United States and other countries began prescribing fenfluramine (Pondimin) or dexfenfluramine (Redux) in combination with phentermine. The combinations known informally as fen-phen (sometimes also written as phen-fen ) or fen-dex had not been approved by the FDA, a process that involves research and hearings. 

Fenfluramine Canal , Ponderal , Ponderax , Pondimin , Redux ... 

Polyethylene glycols, 99 Polyfax, 369 Polymox, 348 Polythiazide, 913 Polytrim, 1049 Poncuronium bromide, 847 Ponderal, 614 Ponderax, 614 Pondimin, 614 Pondocil, 911 Pondocillin, 911 Ponstan, 727 Ponstel, 727 Ponstyl, 727... 

Fenfluramine (approved in 1973, withdrawn in 1997) and phentermine (appetite suppressant approved in 1959 and still available). Wyeth-Ayerst Laboratories, a subsidiary of American Home Products Corp. of Madison, New Jersey, manufactured and marketed fenfluramine under the brand name Pondimin. Wyeth-Ayerst also marketed Redux (dexfenfluramine), which was manufactured for Interneuron Pharmaceuticals. See http //www.fda.gov/cder/news/phen/fenphenpr81597.htm... 

SYNS N-ETHYL-a-METHYL-m-TRIELUOROMETHYL-PHENETHYLANHNE N-ETHYL-a-METHYL-m-(TRIFLUOROMETHYL)PHENETHYLA]VnNE HYDROCHLORIDE FENFLUORAMINE HYDROCHLORIDE PONDERAL PONDERAX PONDIMIN l-(3-TRIFLUOROMETHYLPHENYL)-2-ETHYLAXnNOPROP.YNE HYDROCHLORIDE... 

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