Polynitroaliphatic amines

The Mannich reaction is an excellent route to polynitroaliphatic amines and their derivatives. /3-Nitroalkylamines are formed from the reaction of an amine and aldehyde in the presence of a nitroalkane (Equations 1.4 and A large number of these reactions... 

Frankel and Klager have reported using the Mannich reaction for the condensation of 2,2-dinitroalkanols with ammonia and hydrazine. This method was used to synthesize 2,2,6,6-tetranitro-4-azaheptane (100%) and bis(2,2-dinitropropyl)hydrazine (162) (73%) from the reaction of 2,2-dinitropropanol (25) with ammonia and hydrazine hydrate respectively. This work was later extended to using polynitroaliphatic amines and diamines. " ... 

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See also in sourсe #XX -- [ ]

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