Polycationic Nano- and Microparticles

One of the most popular polycations used to obtain nano/microspheres is chitosan. Nano/microspheres prepared from this polymer were used for the deliveiy of BSA, insulin, a panel of proteins/peptides, heparin, and cyclosporin A.  

Cationic copolymers in the form of nanoparticles were also used to increase water solubility of water-insoluble drugs. This is an important application since one-third of newly discovered drugs are only sparingly soluble in water. Copolymers of 5-Z-amino-8-valerolactone and s-caprolactone were 

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