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Polycarpamine

Polycarpamines A-E (137-141) are unusual sulfur-containing antifungal agents from Polycarpa auzata from the Philippines. The structures were elucidated by interpretation of spectral data [148]. Polycarpine (142), a cytotoxic, dimeric, disulfide alkaloid, the corresponding dihydrochloride (143) and two sulfur-containing related monomers (144-145) were isolated from Polycarpa clavata from Western Australia [149]. Polycarpine (142) was also isolated with two monomers (144,146) from P. auraia from Chuuk [150] and later it was synthesised in three steps from p-methoxyphenacyl bromide [151]. [Pg.640]

Adociaquinones A (492) and B (493) and 3-ketoadociaquinone A (494) were obtained from a sponge Adocia sp. collected in Truk Lagoon (398). Compounds 492 and 493 were synthesized from xestoquinone (399) by heating with hypotaurine. Adociaquinone B (493) was mildly cytotoxic. Polycarpamines A-E (495-499) with a rare, sulfur-containing benzenoid... [Pg.111]

See other pages where Polycarpamine is mentioned: [Pg.836]    [Pg.836]    [Pg.837]    [Pg.837]    [Pg.837]    [Pg.837]    [Pg.112]    [Pg.277]    [Pg.325]    [Pg.492]    [Pg.538]   
See also in sourсe #XX -- [ Pg.640 ]

See also in sourсe #XX -- [ Pg.835 , Pg.836 ]

See also in sourсe #XX -- [ Pg.23 , Pg.25 , Pg.28 , Pg.277 , Pg.640 , Pg.835 , Pg.836 ]

See also in sourсe #XX -- [ Pg.277 ]



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Polycarpamine as disulfide alkaloid

Polycarpamine as sulfur-containing antifungal

Polycarpamine from Polycarpa auzata

Polycarpamine from Polycarpa clavata

Polycarpamine synthesis

Polycarpamines

Polycarpamines

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