Tissue engineering polyacetals

Polymer-Drug Conjugates 221 13.2.5 Polyacetals in Tissue Engineering 228... 

While much recent work has been described to develop polyacetals for drug delivery applications, and historically they have been used as implant materials, more recently, they have been examined as potential scaffold materials in tissue engineering. Implants of Delrin (polyoxymethylene) to repair heart valves were examined, but there was too much swelling in vivo [127]. However, this polyacetal has been used as an orthopedic implant [128] and as an orthopedic implant-coating material [129,130] to interface with bone tissue as this polyacetal has a similar modulus to bone. Ultrasound is used in the diagnosis of osteoporosis and porous polyacetal blocks were found useful to gain insights into bone porosity and ultrasonic properties [131]. 

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