Poly L-isocyanoalanine

Encapsulated CPO in block copolymer polymersomes assembled from polystyrene-b-poly(L-isocyanoalanine-(2-thiophene-3-yl-ethyl)amide) The oxidation of two substrates by the encapsulated CPO was studied while the oxidation of pyrogallol was limited by diffusion into the polymersome, the rate-limiting step for the oxidation of thioansiole was the turnover by the enzyme [46]... 

The amphiphilic block copolymers most conunonly used for the development of nanoreactors consist of hydrophiUc blocks, such as poly(aaylic acid) (PAA), poly(ethylene oxide) (PEO), poly(2-methyl oxazoline) (PMOXA), or poly[L-isocyanoalanine(2-thiophen-3-yl-ethyl)amide] (PIAT), and a hydrophobic block such as polystyrene (PS), polybutadiene (PB), or poly(dimethylsiloxane) (PDMS) [32-35]. Bionanoreactors have been obtained mainly by using polymer vesicles (polymersomes), but there are also a few reports based on other supramolecular assemblies (Table 11.1). 

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