Podand-based and chelating PET sensors

PET-11 (Zinpyr-1), containing fluorescein as a fluorophore, and bis(2-pyridylmethyl)amine as a chelating moiety, has been designed for probing Zn11 in living cells. This compound is indeed cell-permeable and it has essentially no 

The same design principles apply to the magnesium sensors PET-15 and PET-16, in which the recognition moiety has a smaller cavity . 

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