Pneumococcal C-substance

Brundish, D.E. and Baddiley, J. (1968) Pneumococcal C-substance, a ribitol teichoic acid containing choline phosphate. BiochemicalJournal 110, 573-582. 

Heidelberger and Aisenberg240 studied the cross-reaction of the Merck and DuPont polyglucoses with antibodies to pneumococcal C-substance and to type-specific polysaccharides. One of the D-glucose polymers (Merck 52R61I) was separated into a series of fractions on the basis of fractionation with alcohol (isopropyl alcohol and ethanol) and with glacial acetic acid, the most insoluble fraction being called A, and the most soluble, E. The yield, analyses, and reactivity of these fractions with Types IX, XII, XX, and XXII antipneumococcal horse sera are presented in Table VII. 

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