PMX B hemoperfusion

The effect of PMX B hemoperfusion on animal survival was examined in a trial of CLP induced sepsis in 3 day old piglets. Although the treatment was associated... 

In a multicenter prospective trial, Cruz et al. randomized 64 patients with abdominal sepsis to either PMX B or conventional therapy (Cruz et al., 2009). The PMX B hemoperfusion procedure was performed twice. At 72 hours, in the treated group, the MAP was higher, vasopressors requirement lower, and SOFA score improved. The 28-day mortality was 32% in the treated group, significantly lower than the conventional group (53%). 

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