PLIMSTEX Results for CaM and Intermediate Protein-Ligand Binding Species

1 PLIMSTEX Results for CaM and Intermediate Protein-Ligand Binding Species 

The PLIMSTEX titration curve shows that CaM becomes more stable (more hydrogen-bonded) upon Ca-binding (Fig. 11.5A). The formation of CaM-4Ca species is the biggest contributor to the shape of the titration curve and accounts for the largest conformational change in the stepwise Ca binding. The earlier 

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