Pleiocarpamine-type alkaloids

There has only been one reported instance of an uleine-type alkaloid from a Malaysian plant. Undulifoline (136), was obtained from the new Malayan Alstonia species, Alstonia undulifolia Kochummen and Wong, in addition to tetrahydrocantleyine, cantleyine, akuammi-cine, pleiocarpamine, echitamidine, 20-epi-I9 -echitamidine, echitamine and nor-echitamine [109]. 

The knowledge of the key fragmentation routes of eburnamine and some related alkaloids confirmed or elucidated the structures of the alkaloids 11-methoxy-vincamine,100 vincaminine,102 and vinci-nine,102 of the same skeletal type as eburnamine. Alkaloids of the mavacurine-pleiocarpamine group (212)103 are characterized by a key fragment corresponding to the loss of the ester group and... 

Pawelka and Stockigt (5S5) identified eight different indole alkaloids from cell suspension cultures of O. elliptica. The pattern of the alkaloids found was quite different from the above-mentioned results reported by Kuoadio and co-workers (779). The alkaloids identified were tetrahydroal-stonine, cathenamine, pleiocarpamine and two other methoxy-substituted heteroyohimbine alkaloids Corynanthe/heteroyohimbine type), norfluo-rocurarine Strychnos type), and apparicine and epchrosine Aspi-dosperma type). The last mentioned alkaloid was a new compound (729) not known from intact plants. 

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