Platinum anticancer drugs, chemistry

Recent reviews in the field of platinum anticancer drugs focus on platinum-nucleobase chemistry [7], biological processing of platinum-modified DNA [8], trans-platinum anticancer drugs [5], cisplatin and derived anticancer drugs [4,9], proteins and cisplatin [10], trans-diam-mineplatinum(II) and nucleic acids [11], and catalytic activity and DNA [12], just to mention a few. The aim of this review is to explore the chemistry in the interaction of various platinum compounds with nucleic... 

Lock, C. J. L. (1980). Structural studies of the hydrolysis products of platinum anticancer drugs, and their complexes with DNA base. In A. E. Martell (ed.), ACS Symposium Series, Vol. 140 Inorganic Chemistry in Biology and Medicine, pp. 209-24. 

Lippard SJ (1987) Chemistry and molecular biology of platinum anticancer drugs. Pure Appl Chem 59 731-742. 

Rosenberg, B. Platinum Complexes for the Treatment of Cancer. Why the Search goes on. In Cisplatin Chemistry and Biochemistry of a Leading Anticancer Drug Lippert, B., Ed. Wiley-VCH New York, 1999 pp 3-30. 

Based in part on the article Platinum-based Anticancer Drugs by Steven J. Brown, Christine S. Chow Stephen J. Lippard which appeared in the Encyclopedia of Inorganic Chemistry, First Edition. 

N. Farrell, Y. Qu, U. Bierbach, M. Valsecchi, and E. Menta, Structure-activity Relationships Within Di-and Trinuclear Platinum Phase-I Clinical Anticancer Agents, in 30 Years of Cisplatin, Chemistry and Biochemistry of a Leading Anticancer Drug , ed. B. Lippert, Wiley VCH, Weinheim, 1999, p. 479. 

---