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Platinum anticancer drug application

Barefoot, R.R. Speciation of platinum compounds a review of recent applications in studies of platinum anticancer drugs. J. Chromatogr. B 751, 205-211 (2001)... [Pg.391]

Kalayda GV, Zhang G, Abraham T, Tanke HJ, Reedijk J. Application of fluorescence microscopy for investigation of cellular distribution of dinuclear platinum anticancer drugs. J. Med. Chem. 70. 2005 48 5191-5202. [Pg.2179]

Anticancer Drugs Anticancer drugs and their metal complexes appear as cis- and trans-isomers. The ds-isomers of the dichlordiaminoplatin(II) cis-DDP) and the tetrachlordiaminoplatin(IV) are known as the most effective complexes. The former ds-isomer of platinum(Pt II) has a large application in the treatment of cancer of the ovaries and testicles. Trans-complexes have shown toxicity and do not possess non-anticancer action. [Pg.702]

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See also in sourсe #XX -- [ Pg.4 ]



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