Plakortis angulospiculatus

Besides typical cardanol-like structure, Sleeper and Fenical have identified in 1977 navenone, an alkylphenol derivative as a component of trail pheromone of the mollusk Navanax inermis [27]. Another alkylpheno lie derivative, plakinidone, has beed isolated in 1991 from a Caribbean sponge Plakortis angulospiculatus [26]. In 1995 the carboxylic acid derivative of alkylphenol - elenic acid was isolated from the Indonesian sponge Plakinastrella [25]. The structures and formulas of known monohydric phenolic lipids are presented in Fig. (1). 

Monohydric phenols with alkyl chains are rare amongst marine natural products and navenone [27], (Fig. 1-9), is a component of the trail pheromone of the mollusc, Navanax inermis, while plakinidone, (Fig. 1-11), was isolated from the Caribbean sponge, Plakortis angulospiculatus (Plakinidae) [26]. 

Ankisetty, S., Gochfeld, D., Diaz, C., Khan, S.L, and Slattery, M. (2010) Chemical constituents of the deep reef Caribbean sponges Plakortis angulospiculatus and Plakortis halichondrioides and their antiinflammatory adivities. J. Nat. Prod., 73, 1494—1498. 

Huang, X.-H., Van Soest, R Roberge, M and Andersen, R.J. (2004) Spiculoic acids A and B, new polyketides isolated from the Caribbean marine sponge Plakortis angulospiculatus, Org, Lett, 6, 75-78. 

Compagnone, R,S, Pina, I,C, Rangel, H,R, Dagger, F., Suarez, A.I., Reddy, M,V,R, and Faulkner, D,(, (1998) Antileishmanial cychc peroxides from the Palauan sponge Plakortis aff. angulospiculatus. Tetrahedron. 54, 3057-3068,... 

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