4-Piperidino-4-piperidinecarboxamide

A mixture of 84 parts of 3,3-diphenyl-3-cyanopropyl bromide, 41 parts of 4-piperidino4-pi-peridinecarboxamide, 64 parts of sodium carbonate, a small amount of potassium iodide and 1,200 parts of anhydrous toluene was stirred, and heated under reflux for 48 hours. At the end of this time the reaction mixture was allowed to cool to room temperature, and 500 parts of water were added. The resultant precipitate was removed by filtration, and triturated with diisopropyl ether. The crystalline material thus obtained was removed by filtration, and re-crystalli2ed from 320 parts of acetone, to give 1 -(3,3-diphenyl-3-cyanopropyl)4-piperidino-4-piperidinecarboxamide, melting at about 149°C to 150°C. 

Chemical Name l-(3,3-Diphenyl-3-cyanopropyl)-4-piperidino-4-piperidinecarboxamide... 

Chemical Name 1-(3,3-DiphenYl-3-cYanopropYl)4-piperidino-4-piperidinecarboxamide Common Name Pirinitramide Structural Formula ... 

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