Pigmentation genes

Table 1. Pigmentation Genes Act at Different Levels Level Locus/Gene...

Halaban, R., and Moellmann, G. (1990). Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity. Proc. Natl. Acad. Sci. USA 87 4809-4813. 

Mooney, M. et al.. Altered regulation of tomato and tobacco pigmentation genes caused by the... 

Figure 9.2. The inherent metabolic flexibility of the isoprenoid pathway leading to the synthesis of some carotenoid pigments. Genes coding for two enzymes capable of acting on carotenoid structures were introduced into Escherichia coli which had already been transformed to give it the capacity to make p,p-carotene. Both of the two introduced new enzymes (one shown with red arrows and the other with blue arrows) acted on multiple substrates because of their lack of specificity. The resulting matrix of transformations means that nine different products can be made by just two tailoring enzymes. (Adapted from Umeno et al. ° who used data from Misawa et al. °)...

Sturm, R. A., 1998, Human pigmentation genes and their response to UV radiation, Mutat. Res. Rev. 422 69-76. 

Figure 10 Examples of unnatural aromatic polyketides. Libraries of aromatic poly-ketides have been generated using combinations from the actinorhodin, tetracenomycin, frenolicin, griseusin, and whiE spore pigment gene clusters.

Figure 32.29. Recombination Pathways Leading to Color Blindness. Rearrangements in the course of DNA replication may lead to (A) the loss of visual pigment genes or (B) the formation of hybrid pigment genes that encode photoreceptors with anomolous absorption spectra. Because the amino acids most important for determining absorption spectra are in the carboxyl-terminal half of each photoreceptor protein, the part of the gene that encodes this region most strongly affects the absorption characteristics of hybrid receptors. [Adapted from J. Nathans. Neuron 24(1999) 299-312 by permission of Cell Press.]...

Vollroth, D., Nathans, J., and Davis, R. W. (1988) Tandem array of human visual pigment genes at Xq28. Science 240, 1669-1672. 

Mooney M, Desnos T, Harrison K, Jones J, Carpenter R, Coen E (1995) Altered regulation of tomato and tobacco pigmentation genes caused by the delila gene of Antirrhinum. Plant J 7 333-339... 

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