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Pichia angusta

Biotransfonnation pathways have also been used to establish this chiral center (Scheme 7). The bromoacetophenone 27 was mixed with sodium laurel sulfate and added to a microbial culture of Rhodotorula rubra to produce enantiomencally pure alcohol 28 with 95% ee that was eventually converted to (/ )-salmeterol (2). In a similar transformation, the azidoketone 29 was enantioselectively reduced, using the microorganism Pichia angusta, to the alcohol 30 with > 98% ee that was eventually converted to (S)-salmeterol (2). ... [Pg.209]

Recently a novel potent antifungal antibiotic YM-47522 (42), an open-chain (2Z,4 )-dienamide, has been isolated from the culture broth of Bacillus sp. YL-03709B. The compound showed marked antifungal activity against Rhodotorula acuata and Pichia angusta [79]. Its structure... [Pg.391]


See other pages where Pichia angusta is mentioned: [Pg.209]    [Pg.806]    [Pg.808]    [Pg.139]    [Pg.210]    [Pg.431]    [Pg.209]    [Pg.806]    [Pg.808]    [Pg.139]    [Pg.210]    [Pg.431]    [Pg.214]   
See also in sourсe #XX -- [ Pg.21 , Pg.391 ]

See also in sourсe #XX -- [ Pg.391 ]




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