Physiological effects of a2-adrenergic agonists

While this inhibition is very nice and unequivocal, the intracellular events that occur subsequent to receptor stim- 

Although pertussis toxin is a popular tool in signal transduction research, it acts on several G proteins other than G as well, so that the implication of cAMP by toxin inhibition is 

How these effects relate to cAMP or to the Py-subunits of Gj is not known with certainty. 

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