Physicochemical properties of lysozyme

Lysozyme has a tendency to form polymers. Between pH 5 and 9 it occurs predominantly as a dimer (Sophianopoulos and Van Holde, 1964), forming higher polymers above pH 9.0. The enzyme is stable between pH 1.2 and 11.3 (Jirgensons, 1952). Its physicochemical properties are listed in Table 10.16. 

Modification of its lysyl residues with O-methylisourea has no effect (Geschwind and Li, 1957), but acetylation which removes positive charges from the enzyme, affects strongly the enzymic activi- 

Number of amino acid residues 129 Jollte et at, 1963, Canfield, 1963 

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