Phthaloyl-L-glutamic anhydride

The synthetic potential of salt 19 was demonstrated by the synthesis of coprine 23, which was readily obtained from the hydrochloride by acylation with A -phthaloyl-L-glutamic anhydride in tetrahydrofuran in the presence of triethylamine, followed by removal of the blocking group with hydrazine at pH... 

N-Phthaloyl-L-glutamic anhydride This derivative of L-glutamic anhydride can be prepared without racemization as illustrated. The product is useful for... 

In the fourth method phthaloyl-L-glutamic anhydride is condensed with an amine, an amino acid or an amino acid ester with subsequent removal of the phthaloyl group by hydrazinolysis. This method gives exclusively — or mainly the y-derivative (but compare Section VI. 4.). 

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