Phthalazinones aminolysis

Note The indirect aminolysis of tautomeric phthalazinones may be done via halogeno, alkoxy, thioxo, alkylthio, or other such derivatives. Convenient one-pot syntheses are exemplified here. 

Most aminophthalazines have been made by primary synthesis (see Chapter 8), by the addition of amines to alkylphthalazines (Section 9.3.2), by aminolysis of halogenophthalazines (Section 10.3.2), by aminolysis of phthalazinones (Section 11.1.2.4), by aminolysis of alkoxyphthalazines (Section 11.4.2), by aminolysis of alkylthiophthalazines (Section 12.2), or by reduction of nitrophthalazines... 

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