Photolytic cleavage carbamates

Carbonate linkers have been transformed into carbamates and alcohols via cleavage from the solid support. Alcohols 243 can be produced by the addition of TFA/thioanisole to the resin-bound substrates 242 (Scheme 36). They can also be obtained by photolytic cleavage from resins with general linker structure 238 or via cleavage with fluorine reagents from linkers like 239 in Fig. 11 [205,206]. 

Nitrophenyl)ethyl Carbamate. The photolytic removal of this group occurs twice as fast as does the 2-nitrobenzyl carbamate. Additionally, substitution at the alpha carbon increases the rate of cleavage even more. 

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