Phosphorus pentachloride solvent effects

In neutral medium the deuterium solvent isotope effect, (A h2o/ D2o) in the hydrolysis of diaryldiacyloxyspirosulphuranes483, 404-407 has been found to be 1.66. In acidic medium the ratio of catalytic rate constants has been found to be 0.56. Heterocondensed imidazoles 408, are produced in the reaction of N-benzylamides, 409, of nitrogen heterocyclic carboxylic acids with phosphorus pentachloride. Deuterium labelling experiments have been carried out to understand the mechanism of this reaction involving a nitrile ylide species484. 

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